Name: ATF6B抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： ATF6B抗原（重組蛋白）

英文名稱： ATF6B Antigen (Recombinant Protein)

別名： activating transcription factor 6 beta; G13; CREBL1; CREB-RP

儲存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to a region derived from 2-200 amino acids of human ATF6B

技術(shù)規(guī)格

Full name:	activating transcription factor 6 beta
Synonyms:	G13; CREBL1; CREB-RP
Swissprot:	Q99941
Gene Accession:	BC008394
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.

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