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中文名稱：兔抗ALOX5多克隆抗體
英文名稱： Anti-ALOX5 rabbit polyclonal antibody
別 名： 5-LO, 5LPG, LOG5, 5-LOX
相關(guān)類別： 一抗
抗 原： ALOX5
儲 存： 冷凍（-20℃）
宿 主： Rabbit
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ALOX5 |
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Immunogen: |
Fusion protein of human ALOX5 |
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Full name: |
Arachidonate 5-lipoxygenase |
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Synonyms： |
5-LO, 5LPG, LOG5, 5-LOX |
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SwissProt: |
P09917 |
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ELISA Recommended dilution: |
500-5000 |
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IHC positive control: |
Human colon cancer and human thyroid cancer |
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IHC Recommend dilution: |
50-150 |
