購物車
幫助
021-54845833/15800441009
中文名稱：ISCU 抗原（重組蛋白）
英文名稱： ISCU Antigen (Recombinant Protein)
別 名： iron-sulfur cluster assembly enzyme; HML; ISU2; NIFU; NIFUN; hnifU; 2310020H20Rik
儲 存： 冷凍（-20℃）
相關類別： 抗原
概述
|
Fusion protein corresponding to a region derived from 1-167 amino acids of human ISCU |
|
Full name: |
iron-sulfur cluster assembly enzyme |
|
Synonyms: |
HML; ISU2; NIFU; NIFUN; hnifU; 2310020H20Rik |
|
Swissprot: |
Q9H1K1 |
|
Gene Accession: |
BC011906 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1. |
