Name: LEP抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： LEP抗原（重組蛋白）

英文名稱： LEP Antigen (Recombinant Protein)

別名： OB; OBS; LEPD

儲存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Full length fusion protein

技術(shù)規(guī)格

Full name:	leptin
Synonyms:	OB; OBS; LEPD
Swissprot:	P41159
Gene Accession:	BC069323
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.

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