Name: SIAH1 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱(chēng)： SIAH1 抗原（重組蛋白）

英文名稱(chēng)： SIAH1 Antigen (Recombinant Protein)

別名： siah E3 ubiquitin protein ligase 1; SIAH1A

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類(lèi)別：抗原

概述

Fusion protein corresponding to a region derived from 1-282 amino acids of human SIAH1

技術(shù)規(guī)格

Full name:	siah E3 ubiquitin protein ligase 1
Synonyms:	SIAH1A
Swissprot:	Q8IUQ4
Gene Accession:	BC035562
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]

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