購物車
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021-54845833/15800441009
中文名稱： TYR 抗原（重組蛋白）
英文名稱： TYR Antigen (Recombinant Protein)
相關類別：抗原
儲 存： 冷凍（-20℃）
概 述
|
Full name: |
Tyrosinase |
|
Synonyms: |
CMM8; OCA1A; OCAIA; SHEP3 |
|
Swissprot: |
P14679 |
|
Gene Accession: |
BC027179 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. |
