Name: UBE2Q2 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： UBE2Q2 抗原（重組蛋白）

英文名稱： UBE2Q2 Antigen (Recombinant Protein)

別名： ubiquitin conjugating enzyme E2Q family member 2

相關(guān)類別：抗原

儲存： 冷凍（-20℃）

概述

Fusion protein corresponding to a region derived from 176-375 amino acids of human UBE2Q2

技術(shù)規(guī)格

Full name:	ubiquitin conjugating enzyme E2Q family member 2
Swissprot:	Q8WVN8
Gene Accession:	BC017708
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	UBE2Q2 (Ubiquitin-conjugating enzyme E2 Q2) is a 375 amino acid cytoplasmic protein that is involved in ubiquitin-mediated protein degradation. Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). One of several members of the ubiquitin-conjugating enzyme family, UBE2Q2 is an E2 ubiquitin-conjugating enzyme that acts to catalyze the covalent attachment of ubiquitin residues to various proteins. UBE2Q2 expression is detected in invasive epithelial tissue and tumor masses including head and neck squamous cell carcinomas, suggesting a role for UBE2Q2 in carcinogenesis. Two isoforms of UBE2Q2 exist due to alternative splicing events.

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