購物車
幫助
021-54845833/15800441009
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Fusion protein corresponding to a region derived from 34-259 amino acids of human DKK2 |
技術(shù)規(guī)格
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Full name: |
dickkopf WNT signaling pathway inhibitor 2 |
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Synonyms: |
DKK-2 |
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Swissprot: |
Q9UBU2 |
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Gene Accession: |
BC126328 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). |
