購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：兔抗DCUN1D3多克隆抗體
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Background: |
Covalent attachment of NEDD8 to cullins, a process called neddylation, results in nuclear cullin accumulation, which promotes cell growth, migration, and transformation. DCUN1D3 inhibits neddylation of cullins by sequestering them to the plasma membrane, thereby promoting cell differentiation. Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane (PubMed:25349211). When overexpressed in transformed cells, may promote mesenchymal to epithelial-like changes and inhibit colony formation in soft agar (PubMed:25349211). |
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Applications: |
ELISA, WB |
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Name of antibody: |
DCUN1D3 |
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Immunogen: |
Synthetic peptide corresponding to a region derived from 72-85 amino acids of human DCUN1D3 |
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Full name: |
defective in cullin neddylation 1 domain containing 3 |
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Synonyms: |
44M2.4; SCCRO3 |
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SwissProt: |
Q8IWE4 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
34 kDa |
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WB Positive control: |
LO2,231 and A549 cell lysates |
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WB Recommended dilution: |
200-1000 |
