購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)： 兔抗MSH6多克隆抗體
英文名稱(chēng)： Anti-MSH6 rabbit polyclonal antibody
別 名： GTBP, HSAP, HNPCC5
抗 原： MSH6
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
相關(guān)類(lèi)別： 一抗
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. |
|
Applications: |
ELISA, WB, IHC |
|
Name of antibody: |
MSH6 |
|
Immunogen: |
Fusion protein of human MSH6 |
|
Full name: |
mutS homolog 6 |
|
Synonyms: |
GTBP; HSAP; p160; GTMBP; HNPCC5 |
|
SwissProt: |
P52701 |
|
ELISA Recommended dilution: |
1000-2000 |
|
IHC positive control: |
Human tonsil |
|
IHC Recommend dilution: |
10-50 |
|
WB Predicted band size: |
153 kDa |
|
WB Positive control: |
Hela and 293T cells |
|
WB Recommended dilution: |
200-1000 |
