購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)： 兔抗RET(Phospho-Tyr905)多克隆抗體
英文名稱(chēng)： Anti-RET(Phospho-Tyr905) rabbit polyclonal antibody
別 名： ret proto-oncogene; PTC; MTC1; HSCR1; MEN2A;
MEN2B; CDHF12; CDHR16; RET-ELE1
相關(guān)類(lèi)別： 一抗
克隆類(lèi)型： rabbit polyclonal
抗 原： RET(Phospho-Tyr905)
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
技術(shù)規(guī)格
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Background: |
This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of organs and tissues derived from the neural crest. This proto-oncogene can undergo oncogenic activation through both cytogenetic rearrangement and activating point mutations. Mutations in this gene are associated with Hirschsprung disease and central hypoventilation syndrome and have been identified in patients with renal agenesis. |
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Applications: |
WB |
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Name of antibody: |
RET(Phospho-Tyr905) |
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Immunogen: |
Synthetic peptide of human RET |
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Full name: |
ret proto-oncogene |
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Synonyms: |
PTC; MTC1; HSCR1; MEN2A; MEN2B; CDHF12; CDHR16; RET-ELE1 |
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SwissProt: |
P07949 |
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WB Predicted band size: |
124 kDa |
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WB Positive control: |
COS7 whole cell lysates |
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WB Recommended dilution: |
500-1000 |
