購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：兔抗CD40多克隆抗體
英文名稱： Anti-CD40 rabbit polyclonal antibody
別 名： p50; Bp50; CDW40; TNFRSF5
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： CD40
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CD40 |
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Immunogen: |
Synthetic peptide of human CD40 |
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Full name: |
CD40 molecule, TNF receptor superfamily member 5 |
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Synonyms： |
p50; Bp50; CDW40; TNFRSF5 |
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SwissProt: |
P25942 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human liver cancer and Human gastric cancer |
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IHC Recommend dilution: |
100-300 |
