購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：BCOR抗原（重組蛋白）
英文名稱：BCOR Antigen (Recombinant Protein)
儲(chǔ) 存：冷凍（-20℃）
相關(guān)類別：抗原
Fusion protein corresponding to a region derived from 1569-1755 amino acids of human BCOR
概述
技術(shù)規(guī)格
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Full name: |
BCL6 corepressor |
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Synonyms: |
MAA2, ANOP2, MCOPS2 |
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Swissprot: |
Q6W2J9 |
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Gene Accession: |
BC063536 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y. |
