購物車
幫助
021-54845833/15800441009
技術(shù)規(guī)格
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Background: |
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. |
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Applications: |
WB, IHC |
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Name of antibody: |
PKM2 |
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Immunogen: |
Synthetic peptide of human PKM2 |
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Full name: |
pyruvate kinase, muscle, M2 isoform |
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Synonyms: |
PK3; TCB; OIP3; PKM2; CTHBP; THBP1; HEL-S-30 |
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SwissProt: |
P14618 |
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IHC positive control: |
human colon tissue and carcinoma of human kidney tissue; human liver tissue and carcinoma of human liver tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
58 kDa |
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WB Positive control: |
SVT2, MDCK, PC12 cell lysates |
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WB Recommended dilution: |
500-2000 |
