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021-54845833/15800441009
中文名稱： 兔抗MME多克隆抗體
英文名稱： Anti-MME rabbit polyclonal antibody
別 名： NEP, SFE, CD10, CALLA
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： MME
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
MME |
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Immunogen: |
Synthetic peptide of human MME |
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Full name: |
membrane metallo-endopeptidase |
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Synonyms： |
NEP, SFE, CD10, CALLA |
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SwissProt: |
P08473 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human colon cancer and Human lung cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
86 kDa |
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WB Positive control: |
293T cells |
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WB Recommended dilution: |
500-2000 |
