購物車
幫助
021-54845833/15800441009
中文名稱： 兔抗MRPS12多克隆抗體
英文名稱： Anti-MRPS12 rabbit polyclonal antibody
別 名： RPS12; RPMS12; RPSM12; MPR-S12; MT-RPS12
抗 原： MRPS12
儲 存： 冷凍（-20℃） 避光
宿 主： Rabbit
反應(yīng)種屬： Human
相關(guān)類別： 一抗
標(biāo) 記 物： Unconjugate
克隆類型： Unconjugate
技術(shù)規(guī)格
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Background: |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene; all three variants encode the same protein. |
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Applications: |
WB |
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Name of antibody: |
MRPS12 |
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Immunogen: |
Synthesized peptide derived from internal of human MRPS12. |
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Full name: |
mitochondrial ribosomal protein S12 |
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Synonyms： |
RPS12; RPMS12; RPSM12; MPR-S12; MT-RPS12 |
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SwissProt: |
O15235 |
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WB Predicted band size: |
15 kDa |
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WB Positive control: |
K562 cells lysate |
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WB Recommended dilution: |
500-3000 |
