購物車
幫助
021-54845833/15800441009
中文名稱：小鼠抗ATP2A2單克隆抗體
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Background: |
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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Applications: |
WB |
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Name of antibody: |
ATP2A2 |
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Immunogen: |
Fusion protein of human ATP2A2 |
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Full name: |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
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Synonyms: |
DD; DAR; ATP2B; SERCA2 |
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SwissProt: |
P16615 |
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WB Predicted band size: |
115 KD |
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WB Positive control: |
Human muscle tissue lysate |
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WB Recommended dilution: |
200-1000 |
